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Allergy Frontiers: Epigenetics, Allergens and Risk Factors

Condition: BRAND NEW
ISBN: 9784431728016
Author(s): Stephen Holgate
Format: Hardcover
Year: 2009
Publisher: Springer
Dimensions: 157 x 236 x 25 (w x l x h)
Pages: 442
Series: Allergy Frontiers
Series Number: 1

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Description:
The prevalence of allergic diseases and asthma are on the rise in industrialized as well as industrializing countries with a marked impact on the quality of life of patients and a socioeconomic impact to the countries. This book summarizes the most current knowledge on allergic diseases from epidemiology to mechanisms, environmental and genetic factors that influence the development of allergy and asthma clinical aspects, recent therapeutic and preventive strategies as well as future perspectives. The several chapters also highlight the role of eosinophils, mast cells, lymphocytes, dendritic cells, epithelial cells, neutrophils and T cells, adhesion molecules and cytokines/ chemokines in the pathomechanisms of allergic diseases. Also discussed are the impact of infection and innate immunity on allergy, and mucosal immunology of the various target organs and allergy. Among the therapeutic strategies we have included most recent and emerging therapies including allergen-specific immunotherapy and anti-IgE treatment.. The multidisciplinary character of this book is documented by articles from various fields such as environmental, molecular, and cellular biology, allergy, otolaryngology, pulmonology and dermatology. Representing an excellent collection of state-of-the art reviews by world known leaders from the UK, Europe, North America, South America, Australia, Japan and Sout
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