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Solid State Characterization of Pharmaceuticals

Condition: BRAND NEW
ISBN: 9781405134941
Author(s): Paul Royall
Format: Hardcover
Year: 2011
Edition: 3rd
Publisher: John Wiley and Sons Ltd
Dimensions: 174 x 33 x 249 (w x l x h)
Pages: 526

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Description:
Solid form selection is a critical part of the development of a pharmaceutical compound. The presence of a crystalline drug substance provides improved bulk properties, whereas the use of a salt of a pharmaceutical compound can provide enhanced properties such as increased dissolution rate. Owing to different crystal structures, polymorphic forms of a compound have different physical and chemical properties, which can affect the biopharmaceutical properties of a pharmaceutical compound. The selection of the optimum salt and physical form for development utilises a wide range of analytical procedures and laboratory skills. This book provides an up-to-date review of the current techniques used to characterise pharmaceutical solids. It will serve as a vital resource for analysts, and essential reading for scientists involved in solid form selection.

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